COMPARATIVE STUDY OF QUININE PLUS DOXYCYCLIN VERSUS ARTEMETHER PLUS DOXYCYCLIN IN UNCOMPLICATED PLASMODIUM FALCIPARUM MALARIA IN A TERTIARY CARE TEACHING HOSPITAL OF EASTERN INDIA
نویسندگان
چکیده
منابع مشابه
Artesunate plus pyronaridine for treating uncomplicated Plasmodium falciparum malaria
BACKGROUND The World Health Organization (WHO) recommends that people with uncomplicated Plasmodium falciparum malaria are treated using Artemisinin-based Combination Therapy (ACT). ACT combines three-days of a short-acting artemisinin derivative with a longer-acting antimalarial which has a different mode of action. Pyronaridine has been reported as an effective antimalarial over two decades o...
متن کاملArtemether–lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria
The World Health Organization strongly recommends artemisinin-based combination therapy (ACT) regimens for the treatment of uncomplicated Plasmodium falciparum malaria cases in endemic areas. Among the combinations of compounds that are available at present, excellent results have been obtained for the artemisinin derivative artemether, in a combination galenic preparation with lumefantrine (ar...
متن کاملEffectiveness of quinine versus artemether-lumefantrine for treating uncomplicated falciparum malaria in Ugandan children: randomised trial
OBJECTIVE To compare the effectiveness of oral quinine with that of artemether-lumefantrine in treating uncomplicated malaria in children. DESIGN Randomised, open label effectiveness study. SETTING Outpatient clinic of Uganda's national referral hospital in Kampala. PARTICIPANTS 175 children aged 6 to 59 months with uncomplicated malaria. INTERVENTIONS Participants were randomised to re...
متن کاملComparison of oral artesunate and quinine plus tetracycline in acute uncomplicated falciparum malaria.
In Thailand Plasmodium falciparum malaria is highly resistant to available antimalarials. Investigations on the efficacy of existing antimalarials and of alternative drugs are urgently needed. Artesunate has been shown to be effective against falciparum malaria, but is associated with a high recrudescence rate. We have carried out a comparative clinical trial of the standard regimen of quinine ...
متن کاملRandomized comparison of chloroquine plus sulfadoxine-pyrimethamine versus artesunate plus mefloquine versus artemether-lumefantrine in the treatment of uncomplicated falciparum malaria in the Lao People's Democratic Republic.
BACKGROUND Recent clinical trials in the Lao People's Democratic Republic have demonstrated that chloroquine and sulfadoxine-pyrimethamine, which are national malaria treatment policy, are no longer effective in the treatment of uncomplicated Plasmodium falciparum malaria. METHODS A randomized comparison of 3 oral antimalarial combinations--chloroquine plus sulfadoxine-pyrimethamine versus ar...
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ژورنال
عنوان ژورنال: Journal of Drug Delivery and Therapeutics
سال: 2013
ISSN: 2250-1177
DOI: 10.22270/jddt.v3i4.621